Forskolin, an herbal medicine made from the Asiatic coleus plant, may help treat urinary tract infections (UTIs), according to the results of a new study.
Forskolin, a root extract from Coleus forskohlii, has been used for a long time in traditional Asian systems of medicine to treat angina, asthma, bronchitis, epilepsy, insomnia, painful micturation, skin rashes and a wide range of digestive problems. Numerous studies on forskolin have been conducted since the 1970s. Basic science research has revealed several properties of forskolin, which are promising for clinical use.
Researchers from Duke University tested forskolin in female mice with bladder infections caused by E. coli bacteria, which cause most UTIs.
Twenty-four hours after the mice were infected with E. coli, the researchers injected forskolin directly into the mice's bladders or their bellies. For comparison, the scientists injected saltwater into the bladders of other female mice with E. coli bladder infections.
The study found that one day after treatment, the mice in the forskolin group had less E. coli bacteria in their bladders than the mice that received the saltwater shot. Additionally, the forskolin group had lower levels of inflammatory chemicals in their urine.
Researchers also noted that antibiotics get rid of most bacteria that cause UTIs, but some bacteria may hide in the bladder's lining. Forskolin may force those hidden bacteria out of the bladder's lining, where antibiotics could target them.
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